Gene Thrive 2025
Boston, MA
March 24-26, 2025

About Gene Thrive

Welcome to GeneThrive, where innovation meets inspiration in the dynamic realm of gene therapy. As a premier summit in the field, GeneThrive is dedicated to fostering collaboration, sparking creativity, and accelerating progress in genetic medicine.

GeneThrive brings together a diverse community of scientists, clinicians, entrepreneurs, investors, and policymakers, united by a shared passion for harnessing the power of genes to revolutionize healthcare. Our summit serves as a vibrant platform for thought leaders and trailblazers to exchange ideas, share cutting-edge research, and explore emerging trends shaping the future of gene therapy.

With a focus on inclusivity and interdisciplinary collaboration, GeneThrive cultivates a supportive environment where experts from various disciplines come together to address key challenges and seize opportunities in gene therapy. Through engaging keynotes, interactive workshops, insightful panel discussions, and networking opportunities, GeneThrive empowers attendees to drive innovation, overcome obstacles, and make meaningful contributions to the advancement of genetic medicine.

Join us at GeneThrive and embark on a transformative journey where ideas flourish, connections thrive, and the future of gene therapy is shaped by the collective efforts of passionate individuals committed to making a difference.

Gene Thrive 2025 Speakers

Eric B. Kmiec PhD

Executive Director & Chief Scientific Officer, Gene Editing Institute, Christiana Care

Plenary Speaker
Kevin Davies PhD

Executive Editor, The CRISPR Journal; Author, Editing Humanity

Brian O’Mahony

Chief Executive, Irish Haemophilia Society

Cedric Hermans

Professor, Haemostasis and Thrombosis Unit, Division of Haematology, Haemophilia Clinic, Saint-Luc University Hospital

Why Attend Gene Thrive 2025

GeneThrive 2025 offers a unique opportunity for professionals across various sectors to come together and participate in a transformative event focused on gene therapy. Here are several compelling reasons why individuals should attend:

Stay Updated on the Latest Advancements

GeneThrive provides access to cutting-edge research, breakthrough technologies, and innovative therapies in the field of gene therapy. Attendees will gain insights into the latest advancements, emerging trends, and future directions in genetic medicine.

Networking and Collaboration

The summit offers a platform for networking and collaboration among researchers, clinicians, industry leaders, policymakers, and other stakeholders in the gene therapy community. Attendees can forge new partnerships, exchange ideas, and explore opportunities for collaboration on research projects, clinical trials, and commercial ventures.

Professional Development

GeneThrive offers a diverse program featuring keynote speeches, panel discussions, workshops, and interactive sessions designed to enhance professional development. Attendees can expand their knowledge, acquire new skills, and stay at the forefront of their respective fields.

Access to Expertise

The summit brings together leading experts, thought leaders, and key opinion leaders in gene therapy and related disciplines. Attendees will have the opportunity to engage with experts, ask questions, and seek advice on topics ranging from research methodologies to clinical applications to regulatory affairs.

Influence and Impact

GeneThrive provides a platform for individuals to contribute to the advancement of gene therapy and shape the future of healthcare. Attendees can participate in discussions on ethical, legal, and societal implications, advocate for patient-centered approaches, and influence policy decisions that impact the development and implementation of gene therapy technologies.

Inspiration and Motivation

GeneThrive inspires attendees to think creatively, dream big, and envision a future where gene therapy transforms the lives of patients and families affected by genetic diseases. The summit fosters a sense of optimism, excitement, and possibility, motivating attendees to continue their efforts to advance the field of genetic medicine.

Overall, GeneThrive 2025 offers a dynamic and enriching experience for individuals passionate about gene therapy and committed to driving innovation, collaboration, and progress in the field of genetic medicine.

Agenda at a Glance

Session 1: Advancements in Gene Editing Technologies

CRISPR and Beyond: Innovations in Gene Editing:
This session will delve into the latest advancements in gene editing technologies, including CRISPR/Cas9, base editing, and prime editing. Experts will discuss their applications in therapeutic development, challenges, and future prospects.

Precision Gene Editing with Base Editors: Fine-Tuning the Genome: Advances in Base Editing:
This subsession will focus on base editing technologies, which enable precise, single-nucleotide changes in the genome without inducing double-strand breaks. Experts will discuss the principles, applications, and limitations of base editing, as well as recent innovations and future prospects.

Prime Editing: Rewriting the Genetic Code
This subsession will explore prime editing, a revolutionary genome editing technology that enables the precise insertion, deletion, or substitution of DNA sequences with unprecedented accuracy and efficiency. Experts will discuss the underlying mechanisms, applications, and challenges of prime editing, as well as its potential for therapeutic interventions.

Next-Generation Gene Editing Platforms
Description: This subsession will highlight emerging gene editing platforms and technologies that complement or enhance existing tools like CRISPR. Topics may include homing endonucleases, transposon-based systems, and synthetic nucleases, as well as their applications in basic research and therapeutic development.

Session 2: Gene Delivery Systems: Overcoming Barriers

Viral Vectors: Engineering the Perfect Carrier:
This subsession will focus on viral vectors as one of the most commonly used gene delivery systems in gene therapy. Experts will discuss strategies for engineering viral vectors, optimizing their safety and efficiency profiles, and overcoming immune responses and other challenges associated with their use.

Non-Viral Delivery Systems: Breaking the Barrier:
This subsession will explore non-viral gene delivery systems, including liposomes, nanoparticles, polymers, and cell-penetrating peptides. Experts will discuss the advantages, limitations, and recent advancements in non-viral vectors, as well as strategies for enhancing their delivery efficiency and target specificity.

Genome Editing Delivery: CRISPR Carriers:
This subsession will focus on the delivery of CRISPR-Cas systems for genome editing applications. Experts will discuss different delivery strategies, including viral and non-viral approaches, as well as challenges and opportunities for optimizing CRISPR delivery to target cells and tissues.

Targeted Delivery: Precision Medicine Approaches:
This subsession will explore strategies for achieving targeted delivery of gene therapies to specific cells or tissues while minimizing off-target effects. Experts will discuss ligand-mediated targeting, tissue-specific promoters, and other precision medicine approaches for enhancing the specificity and efficacy of gene delivery systems.

Session 3: Clinical Applications of Gene Therapy

Genetic Disorders: Therapeutic Breakthroughs:
This subsession will focus on the clinical applications of gene therapy for treating genetic disorders, such as cystic fibrosis, muscular dystrophy, and sickle cell disease. Experts will discuss recent therapeutic breakthroughs, ongoing clinical trials, and challenges in translating gene therapies from preclinical studies to clinical practice.

Cancer Immunotherapy: Targeting Tumor Cells: Advances in Base Editing:
This subsession will explore the use of gene therapy for cancer immunotherapy, including adoptive cell transfer, chimeric antigen receptor (CAR) T-cell therapy, and oncolytic viruses. Experts will discuss the latest advances, clinical outcomes, and future directions in utilizing gene-based approaches to target and eradicate cancer cells.

Neurodegenerative Diseases: Promising Interventions:
This subsession will examine the potential of gene therapy for treating neurodegenerative diseases, such as Parkinson's disease, Alzheimer's disease, and amyotrophic lateral sclerosis (ALS). Experts will discuss novel gene delivery strategies, gene editing technologies, and emerging therapeutic targets for addressing the underlying causes of neurological disorders.

Infectious Diseases: Gene-Based Strategies:
This subsession will focus on the use of gene therapy for combating infectious diseases, including viral infections, bacterial infections, and emerging pathogens. Experts will discuss gene-based strategies for vaccine development, antiviral therapies, and immune modulation, as well as the potential role of gene editing in targeting infectious agents and enhancing host resistance.

Session 4: Ethical and Societal Implications

Informed Consent and Autonomy
This subsession will explore the ethical principles of informed consent and patient autonomy in the context of gene therapy trials. Experts will discuss challenges in obtaining meaningful consent, ensuring comprehension of risks and benefits, and protecting vulnerable populations participating in clinical research.

Equity and Access
This subsession will examine issues of equity and access in the delivery of gene therapy interventions. Experts will discuss barriers to access, including cost, insurance coverage, and disparities in healthcare delivery, and explore strategies for promoting equitable access to gene therapies for all patients in need.

Privacy and Genetic Data
This subsession will address the ethical and legal challenges surrounding the collection, storage, and use of genetic data in gene therapy research and clinical practice. Experts will discuss privacy concerns, data security risks, and regulatory frameworks for protecting genetic privacy and ensuring responsible data stewardship.

Social and Cultural Implications
This subsession will explore the social and cultural dimensions of gene therapy, including perceptions, beliefs, and values that may influence acceptance or resistance to genetic interventions. Experts will discuss approaches to fostering culturally sensitive and inclusive practices in gene therapy research, education, and healthcare delivery.

Session 5: Future Directions and Emerging Trends

Next-Generation Therapeutic Modalities:
This subsession will highlight emerging therapeutic modalities that complement or extend the capabilities of gene therapy. Experts will discuss innovative approaches such as RNA-based therapies, gene editing in vivo, and synthetic biology, as well as their potential applications and challenges.

Personalized Medicine and Gene Editing:
This subsession will explore the intersection of gene editing technologies and personalized medicine. Experts will discuss advances in genome sequencing, biomarker identification, and patient stratification, as well as the potential of precision gene editing to tailor therapies to the unique genetic makeup of individual patients.

Gene Therapy for Rare Diseases:
This subsession will focus on the role of gene therapy in addressing rare and orphan diseases with unmet medical needs. Experts will discuss strategies for accelerating the development of gene therapies for rare diseases, including regulatory pathways, patient advocacy, and collaborative research efforts.

Regulatory and Policy Landscape:
This subsession will examine the evolving regulatory and policy landscape surrounding gene therapy research, development, and commercialization. Experts will discuss regulatory challenges, policy implications, and future directions for ensuring the safe and ethical implementation of gene therapy technologies.

Quick Links

Organized By

259, Narendra Colony,
Hyderabad, Telangana 502032

About us

At Synergy, we specialize in crafting unparalleled experiences in the dynamic realms of biotechnology and pharmaceuticals. With a steadfast commitment to excellence, innovation, and collaboration, we stand as pioneers in curating transformative events that catalyze growth, foster connections, and drive industry advancement.